Bulletin N°71

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice - Cell Stem Cell - July 2025

Katie A. Matatall et al.

PMID: 40609533

Microglial insulin resistance drives neurodegeneration - Trends in Endocrinology and Metabolism - July 2025

Miao Sun et al.

PMID: 40610268

Excitatory-neuron-derived interleukin-34 supports cortical developmental microglia function - Immunity - July 2025

Benjamin A Devlin et al.

PMID: 40609535

Microglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice - Nature Communications - July 2025

William A. Mills III et al.

PMID: 40595608

Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis - Nature Communications - July 2025

Yixun Su et al.

PMID: 40595567

Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions - Nature Communications - July 2025

Joseph Giorgio et al.

PMID: 39149503

Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer’s disease - Nature Communications - July 2025

Francieli Rohden et al.

PMID: 40593718

Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity - Nature Immunology - June 2025

Siling Du et al.

PMID: 40571738

Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes in vitro - Cell Reports - July 2025

Anna Podleśny-Drabiniok et al.

PMID: 40570367

A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice - Science Translational Medicine - July 2025

Federico Rossari et al.

PMID: 40601779

Thwarting amyloidosis: IL-17 as a disease modifier along the gut/brain axis - Journal of Clinical Investigation - July 2025

Wade K Self et David M Holtzman

PMID: 40590230

Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas - Cell Reports Medicine - July 2025

Sara Labiano et al.

PMID: 40578365

Gut microbiota dysbiosis induced by brain tumors modulates the efficacy of immunotherapy - Cell Reports - June 2025

Hyeon Cheol Kim

PMID: 40578367

Optogenetic vagal nerve stimulation attenuates heart failure by limiting the generation of monocyte-derived inflammatory CCRL2+ macrophages - Immunity - June 2025

Guoqi Li et al.

PMID: 40580954