Bulletin N°70

Microglia promote inflammatory cell death upon neuronal mitochondrial impairment during neurodegeneration - Nature Immunology - June 2025

Guangyan Miao et al.

PMID: 40563011

Granzyme K+ CD8 T cells slow tauopathy progression by targeting microglia - Nature Immunology - June 2025

Hannah D Mason et al.

PMID: 40555833

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway - Immunity - June 2025

Sarah Naguib et al.

PMID: 40555238

Targeting microglial PPARα ameliorates the outcome of ischemic stroke by enhancing interaction with infiltrating peripheral monocytes/macrophages -

Tong Ren et al.

PMID: 40543039

TGFα controls checkpoints in CNS resident and infiltrating immune cells to promote resolution of inflammation - Nature Communications - June 2025

Lena Lößlein et al.

PMID: 40537468

Neuroinflammation across neurological diseases - Science - June 2025

Fu-Dong Shi et al.

PMID: 40536983

Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation - Nature - June 2025

Zachary White et al.

PMID: 40533562

Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD - Nature - June 2025

Ahyeon Hwang et al.

PMID: 40533550

Microglial pruning of glycinergic synapses disinhibits spinal PKCγ interneurons to drive pain hypersensitivity in mice Science - Translational Medicine - June 2025

Yidan Zou et al.

PMID: 40531965

Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models - Science Translational Medicine - June 2025

Miaomiao Sun et al.

PMID: 40531966

Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions - Nature - June 2025

Brian M Andersen et al.

PMID: 40562937

Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection -

Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions - PNAS - June 2025

Haozhe Wang et al.

PMID: 40549903

Three-photon microscopy: an emerging technique for deep intravital brain imaging - Nature Reviews Neuroscience - June 2025

Robert Prevedel et al.

PMID: 40542182