Bulletin N°67

Microglia replacement: from monocytic origin to therapy - Trends in Immunology - May 2025

Jingyi Yang & Qingyun Li

PMID: 40425373

GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy - Nature Neuroscience - May 2025

Zhang-Peng Chen et al.

PMID: 40425792

The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer’s disease - Nature Communications - May 2025

Kitty B Murphy et al.

PMID: 40419479

Protective genetic variants against Alzheimer's disease - Lancet Neurology - May 2025

Claudia Marino et al.

PMID: 40409316

GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration - Neuron - May 2025

Tianjin Shen et al.

PMID: 40409253

Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - Nature Neuroscience - May 2025

Janos Groh et al.

PMID: 40404995

Neuronal lipofuscinosis caused by Kufs disease/CLN4 DNAJC5 mutations but not by a CSPα/DNAJC5 deficiency - Science Advances - May 2025

Santiago López-Begines et al.

PMID: 40397740

Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing - Brain - May 2025

Gael Moquin-Beaudry et al.

PMID: 40417848

 

Glioma-neuronal circuit remodeling induces regional immunosuppression - Nature Communications - May 2025

Takahide Nejo et al.

PMID: 37577659

Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity - Science Advances - May 2025

Lata Adnani et al.

PMID: 40408475

FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma - Nature Communications - May 2025

Michal Beffinger et al.

PMID: 40404625

Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis - Cell - May 2025

Bo Li et al.

PMID: 40403728

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity - Nature - May 2025

Camilo Faust Akl et al.

PMID: 40399681

The case for targeting latent and lytic Epstein-Barr virus infection in multiple sclerosis - Brain - May 2025

Gavin Giovannoni et al.

PMID: 40327539

Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense - Science - May 2025

Rocky M Barilla et al.

PMID: 40403128

From the labs

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Induction of haemodynamic travelling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging - eBioMedicine - June 2025

Mickaël Pereira et al.

PMID: 40435721